tylosin (tylosine) is a macrolide antibiotic obtained from cultures of streptomyces fradiae. the drug is effective against many microorganisms in animals but not in humans.
cox-2-in-2, a selective inducible cox2 inhibitor, exhibits potent inhibition with an ic50 of 0.24 μm. meanwhile, cox-2-in-1 functions as an anti-inflammatory agent, demonstrating both anti-inflammatory and analgesic activities.
10,11-dehydrocurvularin is an antibiotic and a strong activator of the heat shock response. it inhibits the tgf-β signaling pathway and has anti-tumorous activity.
10,12-tricosadiynoic acid is a highly selective and orally active inhibitor of acyl-coa oxidase-1 (acox1). it can treat the high-fat diet- or obesity-induced metabolic diseases by improving mitochondrial lipid and ros metabolism.
10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. it alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
6-benzylaminopurine (6-bap), benzyl adenine or bap is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell division. it is an inhibitor of respiratory kinase in plants, and increases post-harvest life of green vegetables.
11-oxomogroside iia is a cucurbitane glycoside extracted from the fruits of siraitia grosvenorii. it has inhibitory effects against the ebv-ea activation induced by tpa, shows weak inhibitory effects on activation of nor 1, a nitric oxide (no) donor.
13-oxo-9e,11e-octadecadienoic acid, a potent pparα activator derived from tomato juice and an isomer of 9-oxo-oda, exhibits the ability to decrease plasma and hepatic triglyceride levels in obese diabetic mice[1].
amoxicillin (amoxycillin) binds to and inactivates penicillin-binding proteins (pbps) located on the inner membrane of the bacterial cell wall. amoxicillin anhydrous is the anhydrous form of a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. inactivation of pbps interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. this interrupts bacterial cell wall synthesis and results in the weakening of the bact
hexamethonium bromide (hexamethonium dibromide), a specific antagonist of neuronal-type nicotinic achr in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.
9-aminoacridine is a highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with dna. it is also used as an intracellular ph indicator.
flurbiprofen (dl-flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. it has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase.
metyrapone (nsc-25265) is an inhibitor of the enzyme steroid 11-beta-monooxygenase. it is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
metyrapone tartrate is an inhibitor of the steroid 11-beta-monooxygenase enzyme which is used as a test for feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
clofarabine (clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (ic50 = 65 nm) and dna polymerase.
lactitol monohydrate (d-lactitol monohydrate) is a disaccharide analog of lactulose. it has been widely used to treat constipation and hepatic encephalopathy.
erythrosine b (erythrosine i) , a tetraiodofluorescein, is served as a red coloring in some foods (cherries, fish), as a disclosure of dental plaque, and as a stain of some cell types. its structural was similar to thyroxine.